diff --git a/CHANGELOG.md b/CHANGELOG.md
index 1c3b8616..3bb5cec2 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -1,5 +1,15 @@
 # PEtab changelog
 
+## 0.11 series
+
+### 0.11.0 (unreleased)
+
+**Breaking changes**
+* Follow SPEC 0 instead of NEP 29 for minimum supported dependency versions.
+  Require `numpy>=2.2`, and for the `vis` extra, `matplotlib>=3.10` and
+  `scipy>=1.15`
+  (by @dweindl in https://github.com/PEtab-dev/libpetab-python/pull/578)
+
 ## 0.10 series
 
 ### 0.10.0
diff --git a/README.md b/README.md
index d66d3e7e..231c840f 100644
--- a/README.md
+++ b/README.md
@@ -23,7 +23,9 @@ and the easiest way to install it is running
     pip3 install petab
 
 `petab` requires Python>=3.12. We are following
-[NumPy's Python support policy](https://numpy.org/neps/nep-0029-deprecation_policy.html).
+[SPEC 0](https://scientific-python.org/specs/spec-0000/)
+for the minimum supported versions of Python and core dependencies,
+but may keep supporting a Python version until NumPy drops it.
 
 Development versions of the PEtab library can be installed using
 
diff --git a/doc/development.rst b/doc/development.rst
index cf829692..ab4ad2c9 100644
--- a/doc/development.rst
+++ b/doc/development.rst
@@ -23,7 +23,10 @@ remove it earlier.
 Python compatibility
 --------------------
 
-We follow `numpy's Python support policy <https://numpy.org/neps/nep-0029-deprecation_policy.html>`_.
+We follow `SPEC 0 <https://scientific-python.org/specs/spec-0000/>`_
+for the minimum supported versions of Python and core dependencies
+(NumPy, SciPy, Matplotlib, pandas, ...),
+but may keep supporting a Python version until NumPy drops it.
 
 Release process
 ---------------
diff --git a/pyproject.toml b/pyproject.toml
index 05683be8..2fd4ec0c 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -11,7 +11,7 @@ dynamic = ["version", "readme"]
 description = "Parameter estimation tabular data"
 requires-python = ">=3.12"
 dependencies = [
-    "numpy>=2.1",
+    "numpy>=2.2",
     "pandas>=2.3",
     "python-libsbml>=5.17.0",
     "sympy",
@@ -40,9 +40,9 @@ combine = [
     "python-libcombine>=0.2.6",
 ]
 vis = [
-    "matplotlib>=3.6.0",
+    "matplotlib>=3.10",
     "seaborn",
-    "scipy"
+    "scipy>=1.15"
 ]
 reports = [
     "Jinja2",
@@ -81,8 +81,7 @@ doc = [
     "sphinx-rtd-theme>=0.5.1",
     "m2r2",
     "myst-nb>=0.14.0",
-    # https://github.com/spatialaudio/nbsphinx/issues/687#issuecomment-1339271312
-    "ipython>=7.21.0, !=8.7.0",
+    "ipython>=8.30",
     "pysb",
 ]
 dev = [