diff --git a/Include/ceval.h b/Include/ceval.h
index 93cf38ce6e2264a..e69e75d319de168 100644
--- a/Include/ceval.h
+++ b/Include/ceval.h
@@ -122,14 +122,12 @@ PyAPI_FUNC(void) PyEval_ReleaseThread(PyThreadState *tstate);
 #define Py_END_ALLOW_THREADS    PyEval_RestoreThread(_save); \
                  }
 
-/* Masks and values used by FORMAT_VALUE opcode. */
+/* String conversion constants. */
 #define FVC_MASK      0x3
 #define FVC_NONE      0x0
 #define FVC_STR       0x1
 #define FVC_REPR      0x2
 #define FVC_ASCII     0x3
-#define FVS_MASK      0x4
-#define FVS_HAVE_SPEC 0x4
 
 #ifndef Py_LIMITED_API
 #  define Py_CPYTHON_CEVAL_H
diff --git a/Misc/NEWS.d/next/C_API/2026-11-05-16-56-57.gh-issue-160109.Fvs4m2.rst b/Misc/NEWS.d/next/C_API/2026-11-05-16-56-57.gh-issue-160109.Fvs4m2.rst
new file mode 100644
index 000000000000000..3f41492e70c8d92
--- /dev/null
+++ b/Misc/NEWS.d/next/C_API/2026-11-05-16-56-57.gh-issue-160109.Fvs4m2.rst
@@ -0,0 +1,2 @@
+Remove the unused ``FVS_MASK`` and ``FVS_HAVE_SPEC`` macros. They were used by
+the ``FORMAT_VALUE`` opcode, which was removed in Python 3.13.
diff --git a/Tools/build/check_capi_macros_ignored.txt b/Tools/build/check_capi_macros_ignored.txt
index fefec42b7d381a0..1bcc319e1a24228 100644
--- a/Tools/build/check_capi_macros_ignored.txt
+++ b/Tools/build/check_capi_macros_ignored.txt
@@ -69,8 +69,6 @@ FVC_MASK
 FVC_NONE
 FVC_REPR
 FVC_STR
-FVS_HAVE_SPEC
-FVS_MASK
 GETPGRP_HAVE_ARG
 HAVE_ACCEPT
 HAVE_ACCEPT4